By Naveed Sami
This ebook specializes in assisting either dermatologists and non-dermatologists process the remedy of every disorder in a realistic demeanour. each one bankruptcy stories the present literature of remedies for every sickness, score disorder severity, and gives pragmatic directions according to affliction severity at the utilization of obtainable drugs. the present literature doesn't supply powerful guidance. This e-book addresses this deficiency. This e-book might help consultant clinicians in enforcing applicable remedies in accordance with the categorical sickness and its severity, and attainable possible choices in an algorithmic structure. it'll make the administration of those illnesses extra pragmatic according to either the literature and scientific adventure of experts.
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Additional info for Autoimmune Bullous Diseases: Approach and Management
C) Erosions and erythematous plaques on the back of a woman with pemphigus foliaceus and scalp (Fig. 4). Lesions can appear to become confluent (Fig. 5a) or can appear circinate and geometric with pronounced peripheral scale (Fig. 5b). Untreated lesions do not heal, and over weeks to months increase in number. In more severe cases, the lesions can coalesce and resemble an exfoliative erythroderma, involving the entire skin surface. In contrast with pemphigus vulgaris (PV), oral involvement is absent.
This treatment modality may be especially pertinent in photosensitive individuals. Colchicine has also been successfully used in case reports . Similarly, it is felt that for pemphigus patients with anything beyond very mild disease tetracycline antibiotics can be useful adjuncts but rarely successful as monotherapy [79–81]. More unusual treatments reported in the literature include the following. Two cases of milder localized PF have been reported to be treated with topical immunomodulators, tacrolimus and pimecrolmus [82, 83].
6. Moraes ME, Fernandez-Vina M, Lazaro A, et al. An epitope in the third hypervariable region of the DRB1 gene is involved in the susceptibility to endemic pemphigus foliaceus (fogo selvagem) in three different Brazilian populations. Tissue Antigens. 1997;49(1):35–40. 7. Kouskoukis CE, Ackerman AB. What histologic finding distinguishes superficial pemphigus and bullous impetigo? Am J Dermatopathol. 1984;6(2):179–81. 8. Kouskoukis CE, Ackerman AB. Vacuoles in the upper part of the epidermis as a clue to eventuation of superficial pemphigus and bullous impetigo.