Download Analytical Biotechnology by C. van Dijk (Eds.) PDF

By C. van Dijk (Eds.)

ANABIOTEC '92 fascinated with the additional integration of biotechnology and analytical chemistry. the result of this symposium basically validated huge growth may be stated within the software of either traditional and new analytical options, the latter primarily in line with common analytical instruments corresponding to biomolecules. the most subject matters coated in this assembly are fermentation tracking, chromatography, instrumental research, biosensors and bioanalysis

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The composition of the fermentation broth has a major influence on the membrane fouling and, thus, on the decrease of the flux. The filtration system was successfully used for monitoring of two rather different fermentations which involved both aerobic and anaerobic conditions and bacterial as well as yeast cultures. Depending on the filtrate viscosity, the sampling dead time is about 5 min (gluconic acid fermentation) or about 12 min (beer fermentation). To make sure that the samples taken are really representative, the actual sampling times were chosen to be 12 min and 20 min, respectively.

Tsao, Anal. , 62 (1990) 1798. H. Christensen, J. Nielsen and J. Villadsen, Anal. Chim. Acta, 249 (1991) 123. 3 C F . Mandenius, B. Danielsson and B. Mattiasson, Anal. Chim. Acta, 163 (1984) 135. 4 H. Hâkanson, M. Nilsson and B. Mattiasson, Anal. Chim. Acta, 249 (1991) 61. 5 G. Marko-Varga, T. Buttler, L. Gorton and C. Grönsterwall, Chromatographia, 35 (1993) 285. H. R. Kula, Anal. Chim. Acta, 163 (1984) 3. 7 U. Nalbach, H. W. Stamm,W. R. Kula, Anal. Chim. Acta, 213 (1988) 55. A. A. A. Miller, in preparation.

Thanks are also T. Buttler et al. /Anal Chim. Acta 279 (1993) 27-37 due to Mrs. Marianne Stenberg and Ms. Lena Grönberg for the amino acid and organic acid analyses, Dr. Istvan Csiky, Gist Brocades, Strängnäs, Sweden, for the pénicillium broth, and the Swedish Ethanol Development Foundation for the SSL, respectively. The skilful drawing of the filtration module was made by Mr. Ulf Wellmar. Financial support from the National Energy Administration (STEV) and the Swedish Natural Science Research Council (NFR) is gratefully acknowledged.

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